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Sergei Boichuk Selected Research

Topoisomerase II Inhibitors

5/20222-Amino-Pyrrole-Carboxylate Attenuates Homology-Mediated DNA Repair and Sensitizes Cancer Cells to Doxorubicin.
1/20212-APCAs, the Novel Microtubule Targeting Agents Active Against Distinct Cancer Cell Lines.
11/2020Inhibition of AKT-Signaling Sensitizes Soft Tissue Sarcomas (STS) and Gastrointestinal Stromal Tumors (GIST) to Doxorubicin via Targeting of Homology-Mediated DNA Repair.
1/2018Inhibition of fibroblast growth factor receptor-signaling sensitizes imatinib-resistant gastrointestinal stromal tumors to low doses of topoisomerase II inhibitors.

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Sergei Boichuk Research Topics

Disease

14Neoplasms (Cancer)
05/2022 - 01/2011
10Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor)
01/2021 - 08/2013
2Osteosarcoma (Osteogenic Sarcoma)
05/2022 - 01/2021
2Lung Neoplasms (Lung Cancer)
04/2022 - 01/2021
2Prostatic Neoplasms (Prostate Cancer)
03/2022 - 09/2021
2Sarcoma (Soft Tissue Sarcoma)
01/2021 - 11/2020
1Fibrosarcoma
01/2021
1Infections
10/2020
1Disease Progression
06/2020
1Breast Neoplasms (Breast Cancer)
10/2017
1Genetic Translocation (Chromosomal Translocation)
01/2017
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
01/2017
1Residual Neoplasm
08/2013
1Fanconi Anemia (Fanconi's Anemia)
08/2010

Drug/Important Bio-Agent (IBA)

8Imatinib Mesylate (Gleevec)FDA Link
06/2020 - 08/2013
5TubulinIBA
04/2022 - 01/2016
4Topoisomerase II InhibitorsIBA
05/2022 - 01/2018
4infigratinibIBA
03/2022 - 01/2018
3Paclitaxel (Taxol)FDA LinkGeneric
05/2022 - 10/2017
3Doxorubicin (Adriamycin)FDA LinkGeneric
05/2022 - 11/2020
3PyrrolesIBA
05/2022 - 09/2021
3Annexin A5IBA
04/2022 - 01/2021
3Caspase 3 (Caspase-3)IBA
04/2022 - 01/2021
2DNA (Deoxyribonucleic Acid)IBA
05/2022 - 01/2018
2ColchicineFDA LinkGeneric
04/2022 - 09/2021
2Pemetrexed (MTA)FDA Link
03/2022 - 01/2021
2Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA
10/2018 - 01/2018
2Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
12/2017 - 01/2017
2Phosphotransferases (Kinase)IBA
01/2017 - 02/2014
1Heterocyclic Compounds (Compounds, Heterocyclic)IBA
05/2022
1furanIBA
04/2022
1PD 173074IBA
03/2022
1Member 1 Subfamily B ATP Binding Cassette TransporterIBA
03/2022
1calcein AMIBA
03/2022
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
01/2021
1Phosphatidylinositols (Phosphatidylinositol)IBA
11/2020
14,4- difluoro- 4- bora- 3a,4a- diaza- s- indacene (BODIPY)IBA
10/2020
1Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
06/2020
1Fibroblast Growth Factors (Fibroblast Growth Factor)IBA
10/2018
1Antineoplastic Agents (Antineoplastics)IBA
01/2016
1Pharmaceutical PreparationsIBA
02/2014
1Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
02/2014
1Antiviral Agents (Antivirals)IBA
01/2011
1Promyelocytic Leukemia ProteinIBA
01/2011
1ChromatinIBA
08/2010

Therapy/Procedure

9Therapeutics
04/2022 - 02/2014
2Drug Therapy (Chemotherapy)
05/2022 - 10/2017